Knowledge Base › Troubleshooting Atlas › Equipment faults
Microtome handwheel resistance or slipping
Also known as: microtome resistance, handwheel slipping
What it looks like
Blocks may appear unevenly cut or show irregular thickness. Sections may be difficult to obtain consistently.
Where it usually appears: Typically observed during routine sectioning of paraffin-embedded tissue blocks.
Likely causes
- Dirt or debris accumulation in the handwheel mechanism
- Worn or damaged gears
- Improper lubrication of moving parts
- Incorrect adjustment of the handwheel tension
Immediate checks
- Inspect the handwheel for visible debris or obstruction
- Check for loose screws or components
- Test handwheel movement without a block to assess resistance
Corrective action
- Clean the handwheel mechanism thoroughly
- Lubricate the gears and moving parts as per manufacturer guidelines
- Replace worn or damaged components
Preventive action
- Perform regular maintenance and cleaning of the microtome
- Lubricate moving parts at scheduled intervals
- Ensure proper handling and storage of microtome to avoid damage
This atlas is for educational purposes for laboratory professionals. It does not replace your institutional SOPs, manufacturer instructions, validated protocols or pathologist judgment. Adapt any action to your laboratory and equipment.
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