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Knowledge BaseTroubleshooting Atlas › Tissue processing

Retort fails to drain or fill

What it looks like

Tissue processing may be incomplete, leading to poor infiltration or fixation. Slides may show poorly preserved morphology or empty spaces in blocks.

Where it usually appears: Typically observed during routine processing of tissue samples when the retort fails to function properly.

Likely causes
  • Clogged drainage line
  • Faulty pump mechanism
  • Airlock in the system
  • Incorrect fluid levels
  • Malfunctioning sensors
Immediate checks
  • Inspect the drainage line for blockages
  • Check fluid levels in the retort
  • Ensure the pump is operational
Corrective action
  • Clear any clogs in the drainage line
  • Repair or replace faulty pump components
  • Eliminate airlocks by priming the system
Preventive action
  • Regular maintenance of the retort
  • Routine checks of fluid levels and pump operation
  • Training staff on proper operation procedures
Equipment: Tissue processorRelated SOP: Tissue Processing SOP

This atlas is for educational purposes for laboratory professionals. It does not replace your institutional SOPs, manufacturer instructions, validated protocols or pathologist judgment. Adapt any action to your laboratory and equipment.

Unimeditrek supports histopathology laboratories with tissue processors, microtomes, staining and workflow equipment plus service and AMC. Talk to a specialist →

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