Knowledge Base › Troubleshooting Atlas › Tissue processing
Processor vacuum/pressure failure
What it looks like
Tissue may appear poorly infiltrated or have air bubbles in the block.
Where it usually appears: Typically observed during embedding after tissue processing.
Likely causes
- Vacuum pump failure
- Clogged lines or filters
- Improper processor settings
- Power supply issues
- Mechanical failure of the processor
Immediate checks
- Check vacuum pump operation
- Inspect tubing for blockages
- Confirm power supply to the processor
- Verify processor settings
Corrective action
- Repair or replace vacuum pump
- Clear any obstructions in lines
- Adjust processor settings as needed
- Restart the processor if necessary
Preventive action
- Schedule regular maintenance for vacuum system
- Inspect lines and filters routinely
- Train staff on proper processor use
This atlas is for educational purposes for laboratory professionals. It does not replace your institutional SOPs, manufacturer instructions, validated protocols or pathologist judgment. Adapt any action to your laboratory and equipment.
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