Knowledge Base › Troubleshooting Atlas › Floatation & mounting
Coverslip lifts or slides off
What it looks like
The coverslip may be partially detached or completely off the slide, exposing the tissue section.
Where it usually appears: Typically observed after mounting and during storage or transport of slides.
Likely causes
- Inadequate mounting medium application
- Insufficient drying time before coverslipping
- Poor quality of coverslip or slide
- Contamination on slide or coverslip surface
Immediate checks
- Inspect for air bubbles under the coverslip
- Check for proper adhesion of the mounting medium
Corrective action
- Reapply mounting medium and coverslip if necessary
- Store slides in a flat, stable position
Preventive action
- Ensure proper application of mounting medium
- Allow adequate drying time before coverslipping
- Use high-quality coverslips and slides
This atlas is for educational purposes for laboratory professionals. It does not replace your institutional SOPs, manufacturer instructions, validated protocols or pathologist judgment. Adapt any action to your laboratory and equipment.
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