Knowledge Base › Troubleshooting Atlas › Microtomy
Block face will not cut flat (cannot face the block)
What it looks like
The block face appears uneven with visible grooves or ridges, making it difficult to obtain flat sections.
Where it usually appears: Typically seen when preparing paraffin-embedded tissue blocks for microtomy.
Likely causes
- Inadequate embedding of the tissue
- Improper cooling of the block
- Excessive blade wear or dullness
- Incorrect blade angle
- Block temperature too high
Immediate checks
- Inspect the blade for sharpness
- Check the embedding medium for proper polymerization
- Assess the temperature of the block
Corrective action
- Replace or sharpen the microtome blade
- Re-embed the tissue if necessary
- Adjust the angle of the blade during cutting
Preventive action
- Regularly maintain and sharpen blades
- Ensure proper embedding techniques are followed
- Store blocks at optimal temperatures
This atlas is for educational purposes for laboratory professionals. It does not replace your institutional SOPs, manufacturer instructions, validated protocols or pathologist judgment. Adapt any action to your laboratory and equipment.
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